Skip to content
Ona enzyme pet odor eliminator spray bottle — natural pet stain remover

Natural Enzyme Cleaner • 16 oz

Pet Stain & Odor Eliminator
Enzyme Spray

★★★★★ 4.6+ Stars on Amazon

Professional-strength enzyme pet odor eliminator that uses plant-based bacteria and natural essential oils to break down pet urine, stains, and odors at the molecular level. Not masking — permanently eliminating.

Breaks down uric acid crystals that cause recurring smells
Plant-based bacteria + essential oils — no harsh chemicals
Safe for cats, dogs, kids, and every surface in your home
Made in Canada — 30 years of odor science
Buy on Amazon How It Works

Free shipping with Amazon Prime • 100% satisfaction guarantee

Loved by Real Pets

Ona in the Wild

Real Reviews

What Pet Parents Are Saying

★★★★★

Finally something that WORKS

I've tried Nature's Miracle, Angry Orange, vinegar, baking soda — nothing worked on my cat's favorite spot. Ona actually eliminated it. Completely.

Sarah M. Verified Purchase
★★★★★

Safe for my cats — deal-breaker

Most enzyme cleaners have d-limonene which is toxic to cats. Ona doesn't. That alone made it worth trying. Works better than everything else.

Jessica R. Verified Purchase
★★★★★

30 years of science is real

We foster dogs and go through a LOT of cleaner. Switched to Ona 3 months ago and haven't looked back. Handles the worst accidents.

Mike & Dana T. Verified Purchase
★★★★★

No more embarrassing pet smell

I was the friend whose house 'smelled like dog.' Two treatments with Ona and my sister said she couldn't detect anything. Life-changing.

Amanda L. Verified Purchase
★★★★★

Works on hardwood without damage

My golden had a spot by the back door on our hardwood. Other cleaners stripped the finish. Ona cleaned it without any damage.

Chris K. Verified Purchase
★★★★★

The enzyme cleaner vets recommend

Our vet recommended an enzyme cleaner for our senior cat's accidents. Tried Ona based on the ingredients list — no harsh chemicals. Works perfectly.

Dr. Patel household Verified Purchase

The Science

How Does an Enzyme Cleaner Actually Work?

Enzyme cleaners use beneficial bacteria that produce targeted enzymes to break down odor-causing organic compounds. Unlike chemical cleaners that mask smells with fragrance, enzyme cleaners permanently destroy the odor source.

Why Pet Urine Smell Keeps Coming Back

Pet urine contains uric acid, which forms microscopic crystals that bond to carpet fibers and porous surfaces. Regular cleaners remove the liquid but leave these crystals behind. On humid days, the crystals reactivate — that's why the "clean" carpet smells again every summer.

Full science breakdown →
Before and after using Ona enzyme cleaner on carpet pet stain

Versatile Formula

Best Uses for Ona Enzyme Cleaner

Dog Urine on Carpet

Saturate the stain and let Ona sit for 15 minutes. Enzymes break down uric acid crystals deep in carpet fibers and padding.

Cat Urine & Spray

Cat urine is especially concentrated. Apply generously, wait 30 minutes for old stains. Eliminates the smell that attracts re-marking.

Pet Stains on Furniture

Safe for upholstery, couch cushions, and fabric furniture. Spot-test first on delicate materials.

Carpet Pet Stain Remover

Works on fresh and set-in stains. For old stains, apply twice — first breaks the top layer, second reaches deeper.

Litter Box Area Odor

Spray around and under the litter box. Eliminates the embedded ammonia smell that builds up over time.

Hardwood Floor Cleaning

Safe for sealed hardwood. Spray, wait 10 minutes, wipe clean. No residue, no damage.

Ona works on all surfaces — carpet, litter box, hardwood, car, furniture, anything

One Bottle. Every Surface.

Works On Everything.

Carpet, hardwood, furniture, car interiors, litter boxes, pet beds — wherever your pets go, Ona goes. Safe on every surface, tough on every mess.

CarpetHardwoodFurnitureCarLitter BoxFabricsTileDog BedsPet UrineVomitSkunkAnything

If It's Dirty,
It's Gone.

Loved by millions of homes globally since 1995. Free shipping with Prime.

Shop Now on Amazon

Got Questions?

Common Questions About Enzyme Pet Odor Eliminators

What is the best enzyme pet odor eliminator?
Ona is a professional-strength enzyme pet odor eliminator backed by 30 years of odor science. It uses plant-based bacteria to produce enzymes that break down uric acid crystals from pet urine at the molecular level, permanently eliminating odors rather than masking them.
Does Ona work on old pet urine stains?
Yes. For old, set-in pet urine stains, saturate the area thoroughly and let Ona sit for 30+ minutes. The plant-based bacteria continue working after application, breaking down even deeply embedded uric acid crystals. Apply twice for the most stubborn stains.
Is enzyme cleaner safe for cats?
Yes. Ona contains no bleach, ammonia, phthalates, artificial dyes, or synthetic fragrances. The plant-based formula is safe for homes with cats, dogs, and all pets. Allow the treated area to dry before pets access it.
How is Ona different from other pet odor sprays?
Most pet odor sprays use fragrance to mask smells. Ona uses a biological approach: plant-based bacteria produce enzymes that break down odor compounds at the molecular level. This means the smell is permanently eliminated, not covered up.
What surfaces can I use Ona on?
Ona works on carpet, hardwood floors, tile, laminate, upholstery, furniture, pet beds, litter box areas, car interiors, concrete, and fabrics. It's safe for virtually any surface in your home.
See all FAQs →

Eliminate Pet Odors Permanently

Professional enzyme cleaning. Plant-based formula. Safe for your whole family. Free shipping with Prime.

Buy Ona on Amazon